On October 25th 1895, Bishop Giovanni Battista Scalabrini also established the Congregation of the Missionary Sisters of St. Charles, dedicated to the evangelical service on behalf of migrants, whose presence is widespread throughout the world, especially in the neediest countries.

In Piacenza, the Provincial House of the Sisters is located in an ancient complex annexed to the church of San Savino. The first information we have on the present convent of the Scalabrinian Sisters of Saint Charles Borromeo dates back to 1107. In that year, the ancient Basilica of the XII Apostles in Piacenza was completely restored and dedicated to St Savino; a Benedictine monastery was annexed to it and a new cloister was built in 1496. The entire monastic complex was restored, probably to a design by Giovanni Dordoni Del Bruno in the mid-16th century: from 1555 to 1572 the two sides of the previous cloister: the portico and the eastern wing were rebuilt and the monastic cells of the first wing were built.  In 1584, the construction of the staircase to the upper floors, begun the year before, was completed. Further work and the construction of the fourth side of t

he cloister towards the south was completed in the last decade of the century.

At the beginning of the 17th century, the upper floor was built. Between 1627 and 1630, the sacristy and, on the upper floor, the library were built. Between 1729 and 1733, the flats of the father curate and the monastery bursar were fitted out. The Napoleonic suppression in 1810 led to the sale of the monastery, followed by other vicissitudes and changes of use. It was not until 1932 that engineer Ettore Martini purchased the building, restored it and, in 1939, donated it to the Missionary Sisters of St. Charles Borromeo Scalabrinians, who made it their headquarters.